SeungHyun Lee in MATLAB Answers
Letzte Aktivitätam 8 Dez. 2017

I estimated 8 parameters of my glucose-insulin kinetics model(modified model of 'insulindemo.sbproj') using glucose concentration data as response and glucose, insulin doses as input dose data. The estimation was done by 'Fit Data' task of SimBiology. However, there was warning with details; *"Simulation with phi = [222.249598314537 144.778388565053 2.3665676931561 0.00609950427451014 0.156172487611996 0.0142886095746218 0.00444912107474936 1.27397631652191] could not be completed because: Integration Tolerance Not Met. Empty results have been returned for this simulation."* I used 'ode15s(stiff/NDF) solver with RelativeTolerance value of 1.0E-6. and estimation method was 'ga(Constrained optimization using genetic algorithm)' with TerminationTolerance of 1.0E-10 and MaximumGeneration of 800. What is the meaning of this warning message? and how could I treat it? Thank you for your interest.