It seems like in GUIDE you have added an axis and then added a panel on it. Also you added some text boxes and edit boxes on your panel.
Here are 2 steps to fix your issue and make your GUI look beautiful:
- Go to GUIDE app that you have created the project and then delete axis from the background.
- Go to Tools in top menu of GUIDE then select GUI Options... and then select Resize behavior as Proportional from dropdown menu.
So now you can resize your window or make fullscreen by clicking the middle button on the top right corner.