Reinhard Stain Normalization

This approach maps the colour distribution of an over/under stained image to that of a well stained

This approach maps the colour distribution of an over/under stained image to that of a well stained target image. Reinhard presented a method for matching the colour distribution of an image to that of a target image by use of a linear transform in a perceptual colourspace (the lαβ colourspace of Ruderman et al. ) so as to match the means and standard deviations of each colour channel in the two images in that colourspace.

REFERENCES
[1] Derek Magee, Darren Treanor, Doreen Crellin, Mike Shires, Katherine Smith, Kevin Mohee, and Philip Quirke.:Colour normalization in digital histopathology images.
[2] Reinhard, E., Adhikhmin, M., Gooch, B., Shirley, P.: Color transfer between images.