Why am I not able to use 32-bit DLL COM Objects in 64-bit MATLAB?

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I can instantiate a 32-bit COM DLL-file as an In-Process (InProc) ActiveX Server in 32-bit MATLAB:
a = actxserver('MSOSOAP.HttpConnector30')
a =
COM.MSOSOAP_HttpConnector30
However, when I attempt the same in 64-bit MATLAB:
b = actxserver('MSOSOAP.HttpConnector30')
I receive the following error:
ERROR: ??? Server Creation Failed: Class not registered

Accepted Answer

MathWorks Support Team
MathWorks Support Team on 11 Oct 2021
Edited: MathWorks Support Team on 21 Oct 2021
The documentation for MATLAB 7.6 (R2008a) has been updated to incorporate the relevant information. This information can be accessed under the section 'Instantiating a DLL component':
For previous product releases, read below for any possible workarounds:
Microsoft does not support loading 32-bit DLLs or In-Process (InProc) COM Servers into a 64-bit application, or vice-versa. For additional information, please refer to the following resource on MSDN:
This limitation does not apply to COM Automation servers that are EXE-files (e.g. Excel, 32-bit MATLAB etc.). These servers will work as expected.
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