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How to consider steady state concentration of biomarker in Simbiology
The SimBiology app does not currently provide any direct way to automatically fit steady state data. However, if I'm correctly u...

etwa 4 Jahre vor | 0

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make a data plot
This looks to me like a horizontally oriented box plot. You can easily create such plots using boxchart or boxplot. Since you wa...

etwa 4 Jahre vor | 1

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How do I use global solver to estimate parameters in SimBiology R2021A
I would not read too much into this message. It simply explains why the optimization stopped when it did. In and of itself that ...

etwa 4 Jahre vor | 1

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Work with ODE model system in Simbiology
Not silly at all. That's a pretty common question. The easiest and most direct way to convert such a model over to SimBiology is...

mehr als 4 Jahre vor | 1

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Is volume capacity required to fit PK data in simbiology?
Let me first make sure I understand your question. I think you want to estimate the volume of peripheral and central compartment...

mehr als 4 Jahre vor | 0

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Model fitting using different data sets in SimBiology
Would it be possible for you to upgrade to R2021b? There's a new feature in that release that would make it much easier to do wh...

mehr als 4 Jahre vor | 2

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How to assess to the simulation data after the parameter estimation in Simbiology
Hi Jesse, You can get access to the SimData results used in the plot method by calling the fitted method (described here). If y...

mehr als 4 Jahre vor | 0

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Simulation of tissue drug concentration profile with Kp values
If you are looking for an example of how to incorporate tissue partition coefficients into a PBPK model, then perhaps you can us...

mehr als 4 Jahre vor | 0

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How to set boundary conditions for a reaction to occur in SimBiology?
Hi, Take a look at this answer I shared. It's from several years ago, but the information is still accurate. Some additional ti...

mehr als 4 Jahre vor | 0

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Invalid assignment syntax or parse error for event function (Simbiology)
Hi, Events can only assign a value to a component, not to an expression. So your assignment ((syn_CT.PD1_PDL1+syn_CT.PD1_PDL2)/...

mehr als 4 Jahre vor | 0

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How to customize built-in optimization functions in SimBiology without using MATLAB code?
If I understand your question correctly, you are asking how to customie the cost (or objective) function when using a fit progra...

mehr als 4 Jahre vor | 0

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why PSI values are diffrent when nlmefit using ode45 solver compared to when it uses analytical solution?
The reason the results from nlmefit differ significantly is because your ODE solution is not equivalent to your analyitical solu...

mehr als 4 Jahre vor | 0

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Scanning Simbiology variants in Matlab for virtual population simulations
There are lots of ways you could do this. And you certainly could use variants. But I personally would do this by creating a Sim...

mehr als 4 Jahre vor | 0

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How do I generate a rectangular pulse for an input species in Simbiology?
I would not use rules to implement discontinuous changes in a SimBiology model. The ODE solver should be restarted whenever ther...

mehr als 4 Jahre vor | 0

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Error: expected the time data (independent variable) of the data input argument to be finite
This error means that your time data is invalid because it contains non-finite values. Look for infinite or NaN (not a number) v...

mehr als 4 Jahre vor | 0

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use simbiology for radiation dosimetry
SimBiology is primarily designed to model reactions of species in compartments. It can be used to model other problems that are ...

mehr als 4 Jahre vor | 0

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Should plasma membrane be its own compartment?
Yes, I think the simplest approach would be to create separate compartments for each location where you need to consider that sp...

mehr als 4 Jahre vor | 0

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Different units in the same Simbiology model
I would recommend against mixing mass-based units and mole-based units for species participating in the same reaction. In such c...

mehr als 4 Jahre vor | 2

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Status 429 with message "Too Many Requests" in response to NCBI URL
As described here, you are seeing the error because NCBI limits the number of queries from a particular IP address to 3 per seco...

mehr als 4 Jahre vor | 0

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eGPU set up for Simbiology calculation
No, SimBiology does not currently have any built-in support for GPU calculations. I suggest profiling to see what code is takin...

mehr als 4 Jahre vor | 0

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What toolboxes are useful to run with SimBiology?
I recommend simulating your model within SimBiology (that is, using SimBiology's ODE solvers rather than exporting your equation...

mehr als 4 Jahre vor | 0

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Apply Parallel Computing to Simbiology
Hi Jesse, The simplest fix would be to change 'ProgressPlot',true to 'ProgressPlot',false. The issue is that you're trying to c...

mehr als 4 Jahre vor | 2

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Command in Script for Data Comparison
Hi, Are you using the functions sbiofit or sbiofitmixed? If so, you will find RMSE, AIC, and BIC as properties on the first out...

mehr als 4 Jahre vor | 1

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Need help converting berkeley madonna code to matlab code
If you'd like to convert a Berkeley Madonna model to the equivalent SimBiology model, you can try using this converter from the ...

fast 5 Jahre vor | 1

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Steady State in insulindemo
Hi Pierre, Apologies for the long response, but answering your question acurately requires discussing a lot of details, at leas...

fast 5 Jahre vor | 0

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Insulindemo_Change of numerical values in some parameters are not reflected in the simulation
Hi Juliana, Yes, you can change these parameters. However, the values on the parameters themselves are replaced by any values s...

fast 5 Jahre vor | 0

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How to get rid of "Integration Tolerance Not Met"?
If you simulate from the command line, you should see a warning that infinite or NaN (not-a-number) values occur during the simu...

fast 5 Jahre vor | 0

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value of Stomach Glu After Dosing_insulindemo
I believe you are referring to the value of 125 in the variant named "Type 2 diabetic", as shown for example on this page. I bel...

fast 5 Jahre vor | 1

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Cannot parse function hints
When I do something similar in my installation of MATLAB version R2021a, I get a little popup that says "No completions found". ...

fast 5 Jahre vor | 0

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Nucleotides import- not from database
Based on the information you've provided, I would import the data directly from Excel as you currently have it formatted. You ca...

fast 5 Jahre vor | 0

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