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The study of the dynamics of the discrete Klein - Gordon equation (DKG) with friction is given by the equation :
above equation, W describes the potential function :
The objective of this simulation is to model the dynamics of a segment of DNA under thermal fluctuations with fixed boundaries using a modified discrete Klein-Gordon equation. The model incorporates elasticity, nonlinearity, and damping to provide insights into the mechanical behavior of DNA under various conditions.
% Parameters
numBases = 200; % Number of base pairs, representing a segment of DNA
kappa = 0.1; % Elasticity constant
omegaD = 0.2; % Frequency term
beta = 0.05; % Nonlinearity coefficient
delta = 0.01; % Damping coefficient
  • Position: Random initial perturbations between 0.01 and 0.02 to simulate the thermal fluctuations at the start.
  • Velocity: All bases start from rest, assuming no initial movement except for the thermal perturbations.
% Random initial perturbations to simulate thermal fluctuations
initialPositions = 0.01 + (0.02-0.01).*rand(numBases,1);
initialVelocities = zeros(numBases,1); % Assuming initial rest state
The simulation uses fixed ends to model the DNA segment being anchored at both ends, which is typical in experimental setups for studying DNA mechanics. The equations of motion for each base are derived from a modified discrete Klein-Gordon equation with the inclusion of damping:
% Define the differential equations
dt = 0.05; % Time step
tmax = 50; % Maximum time
tspan = 0:dt:tmax; % Time vector
x = zeros(numBases, length(tspan)); % Displacement matrix
x(:,1) = initialPositions; % Initial positions
% Velocity-Verlet algorithm for numerical integration
for i = 2:length(tspan)
% Compute acceleration for internal bases
acceleration = zeros(numBases,1);
for n = 2:numBases-1
acceleration(n) = kappa * (x(n+1, i-1) - 2 * x(n, i-1) + x(n-1, i-1)) ...
- delta * initialVelocities(n) - omegaD^2 * (x(n, i-1) - beta * x(n, i-1)^3);
end
% positions for internal bases
x(2:numBases-1, i) = x(2:numBases-1, i-1) + dt * initialVelocities(2:numBases-1) ...
+ 0.5 * dt^2 * acceleration(2:numBases-1);
% velocities using new accelerations
newAcceleration = zeros(numBases,1);
for n = 2:numBases-1
newAcceleration(n) = kappa * (x(n+1, i) - 2 * x(n, i) + x(n-1, i)) ...
- delta * initialVelocities(n) - omegaD^2 * (x(n, i) - beta * x(n, i)^3);
end
initialVelocities(2:numBases-1) = initialVelocities(2:numBases-1) + 0.5 * dt * (acceleration(2:numBases-1) + newAcceleration(2:numBases-1));
end
% Visualization of displacement over time for each base pair
figure;
hold on;
for n = 2:numBases-1
plot(tspan, x(n, :));
end
xlabel('Time');
ylabel('Displacement');
legend(arrayfun(@(n) ['Base ' num2str(n)], 2:numBases-1, 'UniformOutput', false));
title('Displacement of DNA Bases Over Time');
hold off;
The results are visualized using a plot that shows the displacements of each base over time . Key observations from the simulation include :
  • Wave Propagation: The initial perturbations lead to wave-like dynamics along the segment, with visible propagation and reflection at the boundaries.
  • Damping Effects: The inclusion of damping leads to a gradual reduction in the amplitude of the oscillations, indicating energy dissipation over time.
  • Nonlinear Behavior: The nonlinear term influences the response, potentially stabilizing the system against large displacements or leading to complex dynamic patterns.
% 3D plot for displacement
figure;
[X, T] = meshgrid(1:numBases, tspan);
surf(X', T', x);
xlabel('Base Pair');
ylabel('Time');
zlabel('Displacement');
title('3D View of DNA Base Displacements');
colormap('jet');
shading interp;
colorbar; % Adds a color bar to indicate displacement magnitude
% Snapshot visualization at a specific time
snapshotTime = 40; % Desired time for the snapshot
[~, snapshotIndex] = min(abs(tspan - snapshotTime)); % Find closest index
snapshotSolution = x(:, snapshotIndex); % Extract displacement at the snapshot time
% Plotting the snapshot
figure;
stem(1:numBases, snapshotSolution, 'filled'); % Discrete plot using stem
title(sprintf('DNA Model Displacement at t = %d seconds', snapshotTime));
xlabel('Base Pair Index');
ylabel('Displacement');
% Time vector for detailed sampling
tDetailed = 0:0.5:50; % Detailed time steps
% Initialize an empty array to hold the data
data = [];
% Generate the data for 3D plotting
for i = 1:numBases
% Interpolate to get detailed solution data for each base pair
detailedSolution = interp1(tspan, x(i, :), tDetailed);
% Concatenate the current base pair's data to the main data array
data = [data; repmat(i, length(tDetailed), 1), tDetailed', detailedSolution'];
end
% 3D Plot
figure;
scatter3(data(:,1), data(:,2), data(:,3), 10, data(:,3), 'filled');
xlabel('Base Pair');
ylabel('Time');
zlabel('Displacement');
title('3D Plot of DNA Base Pair Displacements Over Time');
colorbar; % Adds a color bar to indicate displacement magnitude
Updating some of my educational Livescripts to 2024a, really love the new "define a function anywhere" feature, and have a "new" idea for improving Livescripts -- support "hidden" code blocks similar to the Jupyter Notebooks functionality.
For example, I often create "complicated" plots with a bunch of ancillary items and I don't want this code exposed to the reader by default, as it might confuse the reader. For example, consider a Livescript that might read like this:
-----
Noting the similar structure of these two mappings, let's now write a function that simply maps from some domain to some other domain using change of variable.
function x = ChangeOfVariable( x, from_domain, to_domain )
x = x - from_domain(1);
x = x * ( ( to_domain(2) - to_domain(1) ) / ( from_domain(2) - from_domain(1) ) );
x = x + to_domain(1);
end
Let's see this function in action
% HIDE CELL
clear
close all
from_domain = [-1, 1];
to_domain = [2, 7];
from_values = [-1, -0.5, 0, 0.5, 1];
to_values = ChangeOfVariable( from_values, from_domain, to_domain )
to_values = 1×5
2.0000 3.2500 4.5000 5.7500 7.0000
We can plot the values of from_values and to_values, showing how they're connected to each other:
% HIDE CELL
figure
hold on
for n = 1 : 5
plot( [from_values(n) to_values(n)], [1 0], Color="k", LineWidth=1 )
end
ax = gca;
ax.YTick = [];
ax.XLim = [ min( [from_domain, to_domain] ) - 1, max( [from_domain, to_domain] ) + 1 ];
ax.YLim = [-0.5, 1.5];
ax.XGrid = "on";
scatter( from_values, ones( 5, 1 ), Marker="s", MarkerFaceColor="flat", MarkerEdgeColor="k", SizeData=120, LineWidth=1, SeriesIndex=1 )
text( mean( from_domain ), 1.25, "$\xi$", Interpreter="latex", HorizontalAlignment="center", VerticalAlignment="middle" )
scatter( to_values, zeros( 5, 1 ), Marker="o", MarkerFaceColor="flat", MarkerEdgeColor="k", SizeData=120, LineWidth=1, SeriesIndex=2 )
text( mean( to_domain ), -0.25, "$x$", Interpreter="latex", HorizontalAlignment="center", VerticalAlignment="middle" )
scaled_arrow( ax, [mean( [from_domain(1), to_domain(1) ] ) - 1, 0.5], ( 1 - 0 ) / ( from_domain(1) - to_domain(1) ), 1 )
scaled_arrow( ax, [mean( [from_domain(end), to_domain(end)] ) + 1, 0.5], ( 1 - 0 ) / ( from_domain(end) - to_domain(end) ), -1 )
text( mean( [from_domain(1), to_domain(1) ] ) - 1.5, 0.5, "$x(\xi)$", Interpreter="latex", HorizontalAlignment="center", VerticalAlignment="middle" )
text( mean( [from_domain(end), to_domain(end)] ) + 1.5, 0.5, "$\xi(x)$", Interpreter="latex", HorizontalAlignment="center", VerticalAlignment="middle" )
-----
Where scaled_arrow is some utility function I've defined elsewhere... See how a majority of the code is simply "drivel" to create the plot, clear and close? I'd like to be able to hide those cells so that it would look more like this:
-----
Noting the similar structure of these two mappings, let's now write a function that simply maps from some domain to some other domain using change of variable.
function x = ChangeOfVariable( x, from_domain, to_domain )
x = x - from_domain(1);
x = x * ( ( to_domain(2) - to_domain(1) ) / ( from_domain(2) - from_domain(1) ) );
x = x + to_domain(1);
end
Let's see this function in action
▶ Show code cell
from_domain = [-1, 1];
to_domain = [2, 7];
from_values = [-1, -0.5, 0, 0.5, 1];
to_values = ChangeOfVariable( from_values, from_domain, to_domain )
to_values = 1×5
2.0000 3.2500 4.5000 5.7500 7.0000
We can plot the values of from_values and to_values, showing how they're connected to each other:
▶ Show code cell
-----
Thoughts?
I recently had issues with code folding seeming to disappear and it turns out that I had unknowingly disabled the "show code folding margin" option by accident. Despite using MATLAB for several years, I had no idea this was an option, especially since there seemed to be no references to it in the code folding part of the "Preferences" menu.
It would be great if in the future, there was a warning that told you about this when you try enable/disable folding in the Preferences.
I am using 2023b by the way.
In the MATLAB editor, when clicking on a variable name, all the other instances of the variable name will be highlighted.
But this does not work for structure fields, which is a pity. Such feature would be quite often useful for me.
I show an illustration below, and compare it with Visual Studio Code that does it. ;-)
I am using MATLAB R2023a, sorry if it has been added to newer versions, but I didn't see it in the release notes.
Mike
Mike
Last activity am 31 Mai 2024

Research ethics using generative A.I

Dear members, I’m currently doing research on the subject of using Generative A.I. as a digital designer. What our research group would like to know is which ethical issues have a big impact on the decisions you guys and girls make using generative A.I.
Whether you’re using A.I. or not, we would really like to know your vision and opinion about this subject. Please empty your thoughts and oppinion into your answers, we would like to get as much information as possible.
Are you currently using A.I. when doing your job? Yes, what for. No (not yet), why not?
Using A.I., would you use real information or alter names/numbers to get an answer?
What information would or wouldn’t you use? If the client is asking/ordering you to do certain things that go against your principles, would you still do it because order is order? How far would you go?
Who is responsible for the outcome of the generated content, you or the client?
Would you still feel like a product owner if it was co-developed with A.I.?
What we are looking for is that we would like to know why people do or don’t use AI in the field of design and wich ethical considerations they make. We’re just looking for general moral line of people, for example: 70% of designers don’t feel owner of a design that is generated by AI but 95% feels owner when it is co-created.
So therefore the questions we asked, we want to know the how you feel about this.
As far as I know, the MATLAB Community (including Matlab Central and Mathworks' official GitHub repository) has always been a vibrant and diverse professional and amateur community of MATLAB users from various fields globally. Being a part of it myself, especially in recent years, I have not only benefited continuously from the community but also tried to give back by helping other users in need.
I am a senior MATLAB user from Shenzhen, China, and I have a deep passion for MATLAB, applying it in various scenarios. Due to the less than ideal job market in my current social environment, I am hoping to find a position for remote support work within the Matlab Community. I wonder if this is realistic. For instance, Mathworks has been open-sourcing many repositories in recent years, especially in the field of deep learning with typical applications across industries. I am eager to use the latest MATLAB features to implement state-of-the-art algorithms. Additionally, I occasionally contribute through GitHub issues and pull requests.
In conclusion, I am looking forward to the opportunity to formally join the Matlab Community in a remote support role, dedicating more energy to giving back to the community and making the world a better place! (If a Mathworks employer can contact me, all the better~)
David
David
Last activity am 18 Apr. 2024

AI Models Are Improving Every Year

How long until the 'dumbest' models are smarter than your average person? Thanks for sharing this article @Adam Danz
https://sherwood.news/tech/how-do-ai-models-stack-up-vs-humans-on-standardized-benchmarks/
I created an ellipse visualizer in #MATLAB using App Designer! To read more about it, and how it ties to the recent total solar eclipse, check out my latest blog post:
https://www.davidyding.com/navPages/Ellipse
Github Repo of the app (you can open it on MATLAB Online!):
https://github.com/dvfire123/EllipseVisualizer/tree/main
I'm excited to share some valuable resources that I've found to be incredibly helpful for anyone looking to enhance their MATLAB skills. Whether you're just starting out, studying as a student, or are a seasoned professional, these guides and books offer a wealth of information to aid in your learning journey.
Matlab Books
INTRODUCTION TO MATLAB FOR ENGINEERING STUDENTS
A Guide to MATLAB
MATLAB® Notes for Professionals book
These materials are freely available and can be a great addition to your learning resources. They cover a wide range of topics and are designed to help users at all levels to improve their proficiency in MATLAB.
Happy learning and I hope you find these resources as useful as I have!
I found this link posted on Reddit.
https://workhunty.com/job-blog/where-is-the-best-place-to-be-a-programmer/Matlab/
MatGPT was launched on March 22, 2023 and I am amazed at how many times it has been downloaded since then - close to 16,000 downloads in one year. When AI Chat Playground came out on MATLAB Central, I thought surely that people will stop using MatGPT. Boy I was wrong.
In early 2023 I was playing with the new shiny toy called ChatGPT like everyone else but instead of having it tell me jokes or haiku, I wanted to know how I can use it on MATLAB, and I started collecting the prompts that worked. Someone suggested I should turn that into an app, and MatGPT was born with help from other colleagues.
Here is the question - what should I do with it now? Some people suggested I could add other LLMs like Gemini or Claude, but I am more interested in learning how people actually use it.
If you are a MatGPT user, do you mind sharing how you use the app?
Let S be the closed surface composed of the hemisphere and the base Let be the electric field defined by . Find the electric flux through S. (Hint: Divide S into two parts and calculate ).
% Define the limits of integration for the hemisphere S1
theta_lim = [-pi/2, pi/2];
phi_lim = [0, pi/2];
% Perform the double integration over the spherical surface of the hemisphere S1
% Define the electric flux function for the hemisphere S1
flux_function_S1 = @(theta, phi) 2 * sin(phi);
electric_flux_S1 = integral2(flux_function_S1, theta_lim(1), theta_lim(2), phi_lim(1), phi_lim(2));
% For the base of the hemisphere S2, the electric flux is 0 since the electric
% field has no z-component at the base
electric_flux_S2 = 0;
% Calculate the total electric flux through the closed surface S
total_electric_flux = electric_flux_S1 + electric_flux_S2;
% Display the flux calculations
disp(['Electric flux through the hemisphere S1: ', num2str(electric_flux_S1)]);
disp(['Electric flux through the base of the hemisphere S2: ', num2str(electric_flux_S2)]);
disp(['Total electric flux through the closed surface S: ', num2str(total_electric_flux)]);
% Parameters for the plot
radius = 1; % Radius of the hemisphere
% Create a meshgrid for theta and phi for the plot
[theta, phi] = meshgrid(linspace(theta_lim(1), theta_lim(2), 20), linspace(phi_lim(1), phi_lim(2), 20));
% Calculate Cartesian coordinates for the points on the hemisphere
x = radius * sin(phi) .* cos(theta);
y = radius * sin(phi) .* sin(theta);
z = radius * cos(phi);
% Define the electric field components
Ex = 2 * x;
Ey = 2 * y;
Ez = 2 * z;
% Plot the hemisphere
figure;
surf(x, y, z, 'FaceAlpha', 0.5, 'EdgeColor', 'none');
hold on;
% Plot the electric field vectors
quiver3(x, y, z, Ex, Ey, Ez, 'r');
% Plot the base of the hemisphere
[x_base, y_base] = meshgrid(linspace(-radius, radius, 20), linspace(-radius, radius, 20));
z_base = zeros(size(x_base));
surf(x_base, y_base, z_base, 'FaceColor', 'cyan', 'FaceAlpha', 0.3);
% Additional plot settings
colormap('cool');
axis equal;
grid on;
xlabel('X');
ylabel('Y');
zlabel('Z');
title('Hemisphere and Electric Field');
In short: support varying color in at least the plot, plot3, fplot, and fplot3 functions.
This has been a thing that's come up quite a few times, and includes questions/requests by users, workarounds by the community, and workarounds presented by MathWorks -- examples of each below. It's a feature that exists in Python's Matplotlib library and Sympy. Anyways, given that there are myriads of workarounds, it appears to be one of the most common requests for Matlab plots (Matlab's plotting is, IMO, one of the best features of the product), the request precedes the 21st century, and competitive tools provide the functionality, it would seem to me that this might be the next great feature for Matlab plotting.
I'm curious to get the rest of the community's thoughts... what's everyone else think about this?
---
User questions/requests
User-provided workarounds
MathWorks-provided workarounds
David
David
Last activity am 1 Apr. 2024

Prompts Matter

I was in a meeting the other day and a coworker shared a smiley face they created using the AI Chat Playground. The image looked something like this:
And I suspect the prompt they used was something like this:
"Create a smiley face"
I imagine this output wasn't what my coworker had expected so he was left thinking that this was as good as it gets without manually editing the code, and that the AI Chat Playground couldn't do any better.
I thought I could get a better result using the Playground so I tried a more detailed prompt using a multi-step technique like this:
"Follow these instructions:
- Create code that plots a circle
- Create two smaller circles as eyes within the first circle
- Create an arc that looks like a smile in the lower part of the first circle"
The output of this prompt was better in my opinion.
These queries/prompts are examples of 'zero-shot' prompts, the expectation being a good result with just one query. As opposed to a back-and-forth chat session working towards a desired outcome.
I wonder how many attempts everyone tries before they decide they can't anything more from the AI/LLM. There are times I'll send dozens of chat queries if I feel like I'm getting close to my goal, while other times I'll try just one or two. One thing I always find useful is seeing how others interact with AI models, which is what inspired me to share this.
Does anyone have examples of techniques that work well? I find multi-step instructions often produces good results.
Hannah
Hannah
Last activity am 1 Apr. 2024

Solar Eclipse

Although, I think I will only get to see a partial eclipse (April 8th!) from where I am at in the U.S. I will always have MATLAB to make my own solar eclipse. Just as good as the real thing.
Code (found on the @MATLAB instagram)
a=716;
v=255;
X=linspace(-10,10,a);
[~,r]=cart2pol(X,X');
colormap(gray.*[1 .78 .3]);
[t,g]=cart2pol(X+2.6,X'+1.4);
image(rescale(-1*(2*sin(t*10)+60*g.^.2),0,v))
hold on
h=exp(-(r-3)).*abs(ifft2(r.^-1.8.*cos(7*rand(a))));
h(r<3)=0;
image(v*ones(a),'AlphaData',rescale(h,0,1))
camva(3.8)
One of the privileges of working at MathWorks is that I get to hang out with some really amazing people. Steve Eddins, of ‘Steve on Image Processing’ fame is one of those people. He recently announced his retirement and before his final day, I got the chance to interview him. See what he had to say over at The MATLAB Blog The Steve Eddins Interview: 30 years of MathWorking
Before we begin, you will need to make sure you have 'sir_age_model.m' installed. Once you've downloaded this folder into your working directory, which can be located at your current folder. If you can see this file in your current folder, then it's safe to use it. If you choose to use MATLAB online or MATLAB Mobile, you may upload this to your MATLAB Drive.
This is the code for the SIR model stratified into 2 age groups (children and adults). For a detailed explanation of how to derive the force of infection by age group.
% Main script to run the SIR model simulation
% Initial state values
initial_state_values = [200000; 1; 0; 800000; 0; 0]; % [S1; I1; R1; S2; I2; R2]
% Parameters
parameters = [0.05; 7; 6; 1; 10; 1/5]; % [b; c_11; c_12; c_21; c_22; gamma]
% Time span for the simulation (3 months, with daily steps)
tspan = [0 90];
% Solve the ODE
[t, y] = ode45(@(t, y) sir_age_model(t, y, parameters), tspan, initial_state_values);
% Plotting the results
plot(t, y);
xlabel('Time (days)');
ylabel('Number of people');
legend('S1', 'I1', 'R1', 'S2', 'I2', 'R2');
title('SIR Model with Age Structure');
What was the cumulative incidence of infection during this epidemic? What proportion of those infections occurred in children?
In the SIR model, the cumulative incidence of infection is simply the decline in susceptibility.
% Assuming 'y' contains the simulation results from the ode45 function
% and 't' contains the time points
% Total cumulative incidence
total_cumulative_incidence = (y(1,1) - y(end,1)) + (y(1,4) - y(end,4));
fprintf('Total cumulative incidence: %f\n', total_cumulative_incidence);
% Cumulative incidence in children
cumulative_incidence_children = (y(1,1) - y(end,1));
% Proportion of infections in children
proportion_infections_children = cumulative_incidence_children / total_cumulative_incidence;
fprintf('Proportion of infections in children: %f\n', proportion_infections_children);
927,447 people became infected during this epidemic, 20.5% of which were children.
Which age group was most affected by the epidemic?
To answer this, we can calculate the proportion of children and adults that became infected.
% Assuming 'y' contains the simulation results from the ode45 function
% and 't' contains the time points
% Proportion of children that became infected
initial_children = 200000; % initial number of susceptible children
final_susceptible_children = y(end,1); % final number of susceptible children
proportion_infected_children = (initial_children - final_susceptible_children) / initial_children;
fprintf('Proportion of children that became infected: %f\n', proportion_infected_children);
% Proportion of adults that became infected
initial_adults = 800000; % initial number of susceptible adults
final_susceptible_adults = y(end,4); % final number of susceptible adults
proportion_infected_adults = (initial_adults - final_susceptible_adults) / initial_adults;
fprintf('Proportion of adults that became infected: %f\n', proportion_infected_adults);
Throughout this epidemic, 95% of all children and 92% of all adults were infected. Children were therefore slightly more affected in proportion to their population size, even though the majority of infections occurred in adults.
Are you going to be in the path of totality? How can you predict, track, and simulate the solar eclipse using MATLAB?
I would like to propose the creation of MATLAB EduHub, a dedicated channel within the MathWorks community where educators, students, and professionals can share and access a wealth of educational material that utilizes MATLAB. This platform would act as a central repository for articles, teaching notes, and interactive learning modules that integrate MATLAB into the teaching and learning of various scientific fields.
Key Features:
1. Resource Sharing: Users will be able to upload and share their own educational materials, such as articles, tutorials, code snippets, and datasets.
2. Categorization and Search: Materials can be categorized for easy searching by subject area, difficulty level, and MATLAB version..
3. Community Engagement: Features for comments, ratings, and discussions to encourage community interaction.
4. Support for Educators: Special sections for educators to share teaching materials and track engagement.
Benefits:
- Enhanced Educational Experience: The platform will enrich the learning experience through access to quality materials.
- Collaboration and Networking: It will promote collaboration and networking within the MATLAB community.
- Accessibility of Resources: It will make educational materials available to a wider audience.
By establishing MATLAB EduHub, I propose a space where knowledge and experience can be freely shared, enhancing the educational process and the MATLAB community as a whole.
The latest release is pretty much upon us. Official annoucements will be coming soon and the eagle-eyed among you will have started to notice some things shifting around on the MathWorks website as we ready for this.
The pre-release has been available for a while. Maybe you've played with it? I have...I've even been quietly using it to write some of my latest blog posts...and I have several queued up for publication after MathWorks officially drops the release.
At the time of writing, this page points to the pre-release highlights. Prerelease Release Highlights - MATLAB & Simulink (mathworks.com)
What excites you about this release? why?