matlab or simulink generate a stream data by frame

hi! i am new to matlab. now i need to generate a series of stream data . my data size is so big (over 100GB for 10s) so that i can't store that in my memory. so i want create them real time and frame by frame (such as 10000frames ,luckly all the my frame is very similar ). because of same sample rate, all of my frame have a same length. but i don't know which function can solve the problem. and now i just generate about 1s data in memory and the send it out by sumulink.