2D Affine Transform on 2D

I'm attempting to use Affine Transform on an image and x,y coordnates. I made fake data that show the 4 corners of the image and the x,y points. The image points need to be aligned/scaled to fit the x,y points in meters.

%this is the corners of the image:
FC1 = [1 1;
       1 1225;
       3765 1;
       3765 1225];
plot(FC1(:,1),FC1(:,2),'ob')
hold on 

%This is the corners of the x,y points (in meters):
FC2 = [-2.2766 11.73447;
      1.47    -11.79;
      72.266  23.3821;
      75.934 0];

plot(FC2(:,1),FC2(:,2),'or') 
hold off

My hope is that I can scale down the image into the points that represent meters. It is like taking 2 images and scaling them and aligning the corners together. I'm not sure how to use the Affine Transform though... Thank you for the help.