How to completely delete a very small area, the eyes do not look at it, you can see the picture after zooming in.
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Image Analyst on 20 May 2021
I had a more complete answer made up before you deleted your question. So all I'll say now is to use bwareaopen() or bwareafilt().
minAcceptableArea = 100; % pixels or whatever.
binaryImage = bwareaopen(binaryImage, minAcceptableArea); % Keep blobs 100 or larger
binaryImage = bwareafilt(binaryImage, [minAcceptableArea, inf]); % Keep blobs 100 or larger
% Another option if you know how many blobs to expect
binaryImage = bwareaopen(binaryImage, 10); % Keep the 10 largest blobs.