Combine Simulation Scenarios in SimBiology
There are two different methods to combine SimBiology® simulation scenarios that have different doses, different variants, or different sample values for model quantities. After the combination, you get a final set of values (parameter set) that you can use to simulate and explore the model behavior. For instance, you can combine different dosing regimens with different categories of patients (variants) and simulate to explore the efficacy of the drug.
Cartesian Combination
This method is the Cartesian
product of two sets. Suppose doses is a set of
different RepeaDose objects [d1,d2,d3], and
variants is a set of variant objects:
[v1,v2,v3]. The Cartesian combination of
doses and variants is:
doses
x
variants =
(d1,v1),(d2,v1),(d3,v1),(d1,v2),(d2,v2),(d3,v2),(d1,v3),(d2,v3),(d3,v3).
Elementwise Combination
This combination method combines the entries one to one, that is, elementwise. In
other words, the first element of the first set (entry) is combined with the first
element of the second set (entry) and so on. Using the same variables above, the
elementwise combination of doses and
variants is: doses
+
variants = (d1,v1),(d2,v2),(d3,v3). Both sets
must have the same number of elements (samples) for this combination method.
